Anti-Inflammatory Compounds

Anti-inflammatory Effects of NO-releasing Compounds

Anti-allergic and anti-inflammatory compounds from Aglaia andamanica leaves

The leaves from Aglaia andamanica were determined for their anti-allergic and anti-inflammatory effects using RBL2H3 and RAW264.7 cells, respectively. Among the isolated compounds, 24-epi-piscidinol A (5) exhibited the highest antiallergic activity against -hexosaminidase release with an IC50 value of 19.8 M, followed by (-)-yangambin (3, IC50 = 33.8 M), pyramidaglain A (8, IC50 = 37.1 M), ...

Anti-inflammatory and Anti-HIV Compounds from Swertia bimaculata.

Three new compounds (1 - 3), including a sesterterpenoid, aspterpenacid C (1), with an unusual 5/3/7/6/5 pentacyclic skeleton, together with seven known ones (4 - 10), were isolated from the ethanol extract of the traditional Chinese medicinal plant Swertia bimaculata. Their structures were elucidated on the basis of the methods of spectroscopic NMR, MS, and computational chemistry. The structu...

Anti-inflammatory Activity of Extracts and Compounds from Vitex Negundo

RASADAH, M. A., FAREDIAH, A., WONG, C. L. & ONG, B. K. 2005. Antiinflammatory activity of extracts and compounds from Vitex negundo. The antiinflammatory activity of the leaf extract of Vitex negundo was investigated on topical administration using the TPA (tetradecanoylphorbol acetate)-induced mouse ear inflammation model. The crude methanolic extract of V. negundo showed moderate inhibition (...

Immunomodulation and Anti-Inflammatory Effects of Garlic Compounds

The benefits of garlic to health have been proclaimed for centuries; however, only recently have Allium sativum and its derivatives been proposed as promising candidates for maintaining the homeostasis of the immune system. The complex biochemistry of garlic makes it possible for variations in processing to yield different preparations with differences in final composition and compound proporti...